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1.
Front Pharmacol ; 10: 1355, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31866858

RESUMO

Alzheimer disease (AD) is characterized as a chronic neurodegenerative disease associated with aging. The clinical manifestations of AD include latent episodes of memory and cognitive impairment, psychiatric symptoms and behavioral disorders, as well as limited activities in daily life. In developed countries, AD is now acknowledged as the third leading cause of death, following cardiovascular disease and cancer. The pathogenesis and mechanism of AD remain unclear, although some theories have been proposed to explain AD, such as the theory of ß-amyloid, the theory of the abnormal metabolism of tau protein, the theory of free radical damage, the theory of the inflammatory response, the theory of cholinergic damage, etc. Effective methods to predict, prevent or reverse AD are unavailable, and thus the development of new, efficient therapeutic drugs has become a current research hot spot worldwide. The isolation and extraction of active components from natural drugs have great potential in treating AD. These drugs possess the advantages of multiple targets in multiple pathways, fewer side effects and a long duration of curative effects. This article summaries the latest research progress regarding the mechanisms of natural drugs in the treatment of AD, providing a review of the literature and a theoretical basis for improving the clinical treatment of AD.

3.
Zhongguo Zhong Yao Za Zhi ; 38(9): 1335-9, 2013 May.
Artigo em Chinês | MEDLINE | ID: mdl-23944064

RESUMO

Investigation of traditional Chinese medicine resources is the most important issue of the protection and use of traditional Chinese medicine resources. Real-time monitoring of medicinal plant species and coverage of an area are of great significance to the sustainable development of the medicinal plant species diversity and ecological environment. Flower has unique spectral characteristics. Comparing the vegetative stage through the flowering stage it is easier to identify species. The flowering stage is a critical period for identifying species with remote sensing. Carthamus tinctorius as a traditional Chinese medicine resources in XinJiang region, attracted widespread attention in recent years. In this paper, the hyperspectral data of canopy and other vegetation canopy was measured in 2011. The spectral curve was analyzed, the result indicated that C. tinctorius canopy and the canopy after picking showed absorption peak near 770 nm, the first derivative of red edge spectra and invert-Gaussian model were analyzed, the result indicated that there was significant difference between C. tinctorius canopy and other vegetation canopy. The proposed method is designed to provide initial theoretical foundation for growth condition and physiological parameters of C. tinctorius, and make theoretical groundwork for the distribution and elaborate monitoring of C. tinctorius in future.


Assuntos
Carthamus tinctorius/química , Plantas Medicinais/química , Medicina Tradicional Chinesa
4.
Zhongguo Zhong Yao Za Zhi ; 37(17): 2524-9, 2012 Sep.
Artigo em Chinês | MEDLINE | ID: mdl-23236744

RESUMO

Resources survey of traditional Chinese medicine and reserves estimation are found to be the most important issues for the protection and utilization of traditional Chinese medicine resources, this paper used multi-spatial resolution remote sensing images (RS) , geographic information systems (GIS) and global positioning system (GPS) , to establish Scutellaria resources survey of 3S data platform. Combined with the traditional field survey methods, small-scale habitat types were established based on different skullcap reserve estimation model, which can estimate reserves of the wild Scutellaria in Beijing-Tianjin-Hebei region and improve the estimation accuracy. It can provide an important parameter for the fourth national survey of traditional Chinese medicine resources and traditional Chinese medicine reserves estimates based on 3S technology by multiple spatial scales model.


Assuntos
Conservação dos Recursos Naturais , Plantas Medicinais/crescimento & desenvolvimento , Scutellaria/crescimento & desenvolvimento , China , Sistemas de Informação Geográfica , Plantas Medicinais/química , Tecnologia de Sensoriamento Remoto , Scutellaria/química
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